Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events A Systematic Review and Meta-analysis JAMA. 2019;321(3):277-287. Abstract ◯重要 ・心血管の1次予防としてのアスピリンの役割はcontroversialで、潜…

Early extubation followed by immediate noninvasive ventilation vs. standard extubation in hypoxemic patients: a randomized clinical trial Intensive Care Med (2019) 45:62–71 Abstract ◯目的 ・NIVは高二酸化炭素血症の患者でinvasive mechanical …

Intraaortic Balloon Pump in Cardiogenic Shock Complicating Acute Myocardial Infarction Long-Term 6-Year Outcome of the Randomized IABP-SHOCK II Trial Circulation. 2019;139:395–403. Abstract ◯背景 ・心原性ショックにおけるIABPはIABP-SHOCKⅡ t…

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura NEJM Abstract ◯背景 ・後天性TTPにおいて、 the von Willebrand factor–cleaving protease ADAMTS13のimmune-mediated deficiencyは血小板や微小血栓に対するvon Willebrand fact…