Prevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest the Antibio-therapy during Therapeutic Hypothermia to Prevent Infectious Complications (ANTHARTIC) trial. NEJM P：初期波形がshockable rhythmの院外心停止で32-34度のTTM…

Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease NEJM ○PICO P： left main coronary artery disease of low or intermediate anatomical complexity (according to assessment at the participating centers)(N=1905) eligible：sten…

Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure A Randomized Clinical Trial JAMA ○PICO P：high risk of extubatio…

Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm The objective of the Therapeutic Hypothermia after Cardiac Arrest in Nonshockable Rhythm (HYPERION) trial NEJM ○PICO P：18歳以上のnonshockable rhythm(院内でも院外…